Avenanthramide A is an orally active phytoalexin that targets the RNA helicase DDX3 with a KD of 8.8 µM. Avenanthramide A induces mitochondrial swelling and increased ROS production, and triggers apoptosis in CRC cells. Avenanthramide A inhibits smooth muscle cell proliferation and enhances nitric oxide production. Avenanthramide A can be used in research on colorectal cancer and atherosclerosis[1][2].
Molecular Weight:
299.28
Purity:
98.35
CAS Number:
[108605-70-5]
Formula:
C16H13NO5
Target:
Apoptosis,DNA/RNA Synthesis,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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