Fluorizoline selectively and directly binds to prohibitin 1 (PHB1) and 2 (PHB2), and induces apoptosis. Fluorizoline reduces chronic lymphocytic leukemia (CLL) cell viability through the upregulation of NOXA and BIM. Fluorizoline exerts antitumor action in a p53-independent manner[1].
Molecular Weight:
362.20
Purity:
99.77
CAS Number:
[1362243-70-6]
Formula:
C15H8Cl2F3NS
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound
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