JNJ-63576253 (TRC-253) is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 can be used for the research of castration-resistant prostate cancer (CRPC)[1].
Molecular Weight:
538.97
Purity:
99.22
CAS Number:
[2110428-64-1]
Formula:
C23H22ClF3N6O2S
Target:
Androgen Receptor
Application Notes:
MCE Product type: Reference compound
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