Tenivastatin (sodium), Simvastatin Impurity A (sodium)
Simvastatin hydroxy acid (Tenivastatin) sodium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin hydroxy acid sodium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin hydroxy acid sodium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1][2].
Molecular Weight:
458.56
Purity:
99.86
CAS Number:
[101314-97-0]
Formula:
C25H39NaO6
Target:
HMG-CoA Reductase (HMGCR),Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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