Z62954982 (ZINC08010136) is a potent, selective and cell-permeable Rac1 (IC50=12 µM) inhibitor that is 4 times more effective than NSC23766 (HY-15723A) (IC50=50 µM). Z62954982 disrupts the Rac1/Tiam1 complex and decreases cytoplasmic levels of active Rac1 (GTP-bound Rac1), without affecting the activity of other Rho GTPases (such as Cdc42 or RhoA)[1][2].
Molecular Weight:
415.46
Purity:
99.38
CAS Number:
[1090893-12-1]
Formula:
C20H21N3O5S
Target:
Ras
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
