MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction. MID-1 disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake[1].
Molecular Weight:
293.30
Purity:
99.36
CAS Number:
[312608-54-1]
Formula:
C12H11N3O4S
Target:
Insulin Receptor
Application Notes:
MCE Product type: Reference compound
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