(E)-FOBISIN101 is a 14-3-3 protein inhibitor (14-3-3gamma IC50 = 16.4 µM, 14-3-3zeta IC50 = 9.3 µM). (E)-FOBISIN101 inhibits the binding of 14-3-3 with Raf-1 and proline-rich AKT substrate, and neutralizes the ability of 14-3-3 to activate exoenzyme S ADP-ribosyltransferase. (E)-FOBISIN101 can be used for 14-3-3-mediated cancer research[1].
Molecular Weight:
461.21
Purity:
95.63
CAS Number:
[1370281-06-3]
Formula:
C15H11N3Na3O8P
Target:
Ser/Thr Protease
Application Notes:
MCE Product type: Reference compound
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