SPR inhibitor 3 (SPRi3) is a potent sepiapterin reductase (SPR) inhibitor. SPR inhibitor 3 (SPRi3) displays high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2 µM). SPR inhibitor 3 (SPRi3) reduces neuropathic and inflammatory pain through a reduction of BH4 levels[1][2][3].
Molecular Weight:
262.30
Purity:
99.01
CAS Number:
[1292285-54-1]
Formula:
C14H18N2O3
Target:
Carbonyl Reductase
Application Notes:
MCE Product type: Reference compound
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