NAE-IN-M22 is a potent, selective and reversible inhibitor of NEDD8 activating enzyme (NAE), with potency in micromolar range. NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo[1].
Molecular Weight:
363.32
Purity:
99.94
CAS Number:
[864420-54-2]
Formula:
C20H24Cl2N2
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound
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