5-NIdR (1-(beta-D-2-Deoxyribofuranosyl)-5-nitroindole), an artificial nucleoside, exhibits the ability to inhibit the replication of DNA lesions generated by Temozolomide (HY-17364). 5-NIdR induces cancer cells apoptosis and arrests cell cycle at G0 phase. 5-NIdR enhances Temozolomide anti-tumor efficacy in murine glioblastoma model[1].
Molecular Weight:
278.26
Purity:
98
CAS Number:
[191421-10-0]
Formula:
C13H14N2O5
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound
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