YLT-11 is a potent, selective and orally active PLK4 inhibitor with Kd values of >10000, 653, >10000, 5.2 nM for PLK1, PLK2, PLK3, PLK4, respectively. YLT-11 shows antiproliferative activity. YLT-11 induces Apoptosis and cell cycle arrest at G2/M phase. YLT-11 show anticancer activity[1].
Molecular Weight:
412.49
Formula:
C24H24N6O
Target:
Apoptosis,Polo-like Kinase (PLK)
Application Notes:
MCE Product type: Reference compound
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