ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1, NR5A2) inverse agonist with an IC50 of 3.7 µM. ML-180 is inactive for steroidogenic factor-1 (SF-1, NR5A1, IC50>10 µM). ML-180 has the potential for LRH-1-dependent cancers[1][2].
Molecular Weight:
388.89
Purity:
99.96
CAS Number:
[863588-32-3]
Formula:
C20H25ClN4O2
Target:
Orphan Nuclear Receptor,Orphan Receptor
Application Notes:
MCE Product type: Reference compound1
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