alpha-Fluoromethylhistidine (dihydrochloride), CAS [[81839-27-2]]

Product Overview

• Article Name: alpha-Fluoromethylhistidine (dihydrochloride), CAS [[81839-27-2]]
• Biozol Catalog Number: MCE-HY-115822
• Supplier Catalog Number: HY-115822
• Alternative Catalog Number: MCE-HY-115822-5MG,MCE-HY-115822-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

alpha-Fluoromethylhistidine dihydrochloride is an orally active histidine decarboxylase inhibitor. alpha-Fluoromethylhistidine dihydrochloride depletes histamine in enterochromaffin-like (ECL) cells, reduces the number and volume density of secretory vesicles in ECL cells, and does not affect histamine storage in mast cells. alpha-Fluoromethylhistidine dihydrochloride abolishes Omeprazole (HY-B0113)-induced vacuolization of ECL cells and decreases gastrin-induced histamine efflux from ECL cells. alpha-Fluoromethylhistidine dihydrochloride does not alter the granular characteristics of ECL cells, omeprazole-induced hypertrophy of ECL cells, gastrin-induced pancreastatin-like immunoreactivity efflux, nor does it affect gastric acid secretion induced by histamine or vagal stimulation. alpha-Fluoromethylhistidine dihydrochloride inhibits basal and gastrin-stimulated gastric acid secretion, reduces acid output induced by gastrin+IBMX (HY-12318), but does not directly affect acid generation in isolated parietal cells[1][2][3][4].

Product Properties

• Molecular Weight: 260.09
• Purity: 99.1
• CAS Number: [81839-27-2]
• Formula: C7H12Cl2FN3O2
• Target: Amino Acid Decarboxylase

Application Notes

• Application Notes: MCE Product type: Reference compound1