Ap44mSe is a selenosemicarbazone that effectively depletes cellular Fe, resulting in transferrin receptor-1 up-regulation, ferritin down-regulation, and increased expression of the potent metastasis suppressor, N-myc downstream regulated gene-1. Ap44mSe forms redox active Cu complexes that target the lysosome to induce lysosomal membrane permeabilization[1].
Molecular Weight:
269.20
CAS Number:
[79514-49-1]
Formula:
C10H14N4Se
Target:
Others
Application Notes:
MCE Product type: Reference compound1
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