SR-1114 is a PROTAC degrader targeting ENL. SR-1114 degrades ENL in a CRBN-dependent manner and selectively downregulates ENL target genes. SR-1114 can promote the differentiation of acute myeloid leukemia cells. SR-1114 can be used in tumor research. (Pink: ENL ligand (HY-145409), Black: Linker, Blue: E3 Ligand (HY-14658))[1].
Molecular Weight:
830.86
Purity:
99.04
CAS Number:
[2769141-82-2]
Formula:
C39H42N8O11S
Target:
Epigenetic Reader Domain,PROTACs
Application Notes:
MCE Product type: Reference compound
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