AChE-IN-11 (compound 5C) is a triple inhibitor targeting AChE/MAO-B/BACE1 (IC50=7.9 µM, 9.9 µM, 8.3 µM, respectively) and a selective metal ion chelators. AChE-IN-11 exhibits mixed AChE inhibitory effects, binding to both CAS and PAS of AChE. AChE-IN-11 also exhibits good antioxidant activity (ORAC=2.5 eq) and potential neuroprotective effects in Alzheimers disease[1].
Molecular Weight:
336.43
Formula:
C18H28N2O4
Target:
Cholinesterase (ChE)
Application Notes:
MCE Product type: Reference compound1
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