Glumetinib (SCC244) is a highly selective, orally bioavailable, ATP-competitive c-Met inhibitor with an IC50 of 0.42 nM. Glumetinib has greater than 2400-fold selectivity for c-Met over those 312 kinases evaluated, including the c-Met family member RON and highly homologous kinases Axl, Mer, TyrO3. Antitumor activity[1].
Molecular Weight:
459.48
Purity:
99.94
CAS Number:
[1642581-63-2]
Formula:
C21H17N9O2S
Target:
c-Met/HGFR
Application Notes:
MCE Product type: Reference compound
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