BPR1J-340 is a potent FLT3 inhibitor with an IC50 of ~25 nM. BPR1J-340 inhibits the phosphorylation of FLT3 and STAT5 and triggered apoptosis in FLT3-ITD+ acute myeloid leukemia (AML) cells. BPR1J-340 exhibits significant anti-tumor activities[1].
Molecular Weight:
542.63
CAS Number:
[1395051-72-5]
Formula:
C29H34N8O3
Target:
Apoptosis,FLT3
Application Notes:
MCE Product type: Reference compound1
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