7-Hydroxycoumarinyl arachidonate (7-HCA) is a fluorogenic substrate of cytosolic phospholipase A2 (PLA2). 7-Hydroxycoumarinyl arachidonate is also a fluorogenic substrate for monoacylglycerol lipase (MAGL). MAGL protein catalyzes the hydrolysis of 7-Hydroxycoumarinyl arachidonat to generate Arachidonic acid (AA) and the highly fluorescent 7-hydroxyl coumarin (7-HC, HY-N0573). Release of 7-HC can be measured using a fluorometer[1][2][3].
Molecular Weight:
448.59
Purity:
99.19
CAS Number:
[161180-11-6]
Formula:
C29H36O4
Target:
MAGL,Phospholipase
Application Notes:
MCE Product type: Reference compound1
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