Ceranib-2 is a potent and nonlipid ceramidase inhibitor that inhibits cellular ceramidase activity with an IC50 of 28 µM in SKOV3 cells. Ceranib-2 induces the accumulation of multiple ceramide species, decreases levels of sphingosine and sphingosine-1-phosphate (S1P), and induces cell apoptosis. Anticancer activity[1][2].
Molecular Weight:
381.42
Purity:
98.92
CAS Number:
[1402830-75-4]
Formula:
C25H19NO3
Target:
Apoptosis,LPL Receptor
Application Notes:
MCE Product type: Reference compound1
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