SKLB70326 is a small molecule inhibitor of cell cycle progression that induces cell cycle arrest and apoptosis in human hepatocellular carcinoma cells. SKLB70326 is involved in downregulating cyclin-dependent kinase (CDK) 2, CDK4, and CDK6, while also activating PARP, caspase-3, caspase-9, and Bax, and downregulating Bcl-2.
Molecular Weight:
299.35
CAS Number:
[1257317-77-3]
Formula:
C15H13N3O2S
Target:
Apoptosis,Bcl-2 Family,Caspase,CDK,PARP
Application Notes:
MCE Product type: Reference compound1
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