Amelparib (JPI-289 free base) is a potent, orally active, and water-soluble inhibitor of PARP-1. Amelparib inhibits PARP-1 activity (IC50=18.5 nM) and cellular PAR formation (IC50=10.7 nM) in the nanomolar range. Amelparib is a potential neuroprotective agent. Amelparib has the potential for the research of acute ischaemic stroke[1].
Molecular Weight:
343.42
Purity:
99.17
CAS Number:
[1227156-72-0]
Formula:
C19H25N3O3
Target:
PARP
Application Notes:
MCE Product type: Reference compound1
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