Amelparib (JPI-289) hydrochloride is a potent, orally active, and water-soluble inhibitor of PARP-1. Amelparib hydrochloride inhibits PARP-1 activity (IC50 = 18.5 nM) and cellular PAR formation (IC50 = 10.7 nM). Amelparib hydrochloride is a potential neuroprotective agent. Amelparib hydrochloride has the potential for the research of acute ischaemic stroke[1].
Molecular Weight:
379.88
Purity:
98.37
Formula:
C19H26ClN3O3
Target:
PARP
Application Notes:
MCE Product type: Reference compound1
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