(2S,3R)-LP99 is a potent and selective BRD7 and BRD9 inhibitor with an KD of 99 nM for BRD9. (2S,3R)-LP99 inhibits the association of BRD7 and BRD9 to acetylated histones in vitro and in cells. (2S,3R)-LP99 demonstrates that BRD7/9 plays a role in regulating pro-inflammatory cytokine secretion[1].
Molecular Weight:
516.05
Purity:
99.4
CAS Number:
[1808948-28-8]
Formula:
C26H30ClN3O4S
Target:
Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound1
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