Hyperforin is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin modulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels and triggers adipose tissue thermogenesis via the Dlat-AMPK signaling axis to suppress obesity. Hyperforin also shows diverse pharmacological activities including anti-depression, anti-tumor, anti-dementia, anti-diabetes. Hyperforin modulates gammadelta T cells to secret IL-17alpha, improves Imiquimod (HY-B0180)-induced psoriasis-like mice model[1][2][3][4][5][6].
Molecular Weight:
536.78
CAS Number:
[11079-53-1]
Formula:
C35H52O4
Target:
Calcium Channel,TRP Channel
Application Notes:
MCE Product type: Natural Products
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