AZT triphosphate (3-Azido-3-deoxythymidine-5-triphosphate) TEA is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TEA exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate TEA also inhibits the DNA polymerase of HBV. AZT triphosphate TEA activates the mitochondria-mediated apoptosis pathway[1][2][3].
Formula:
C10H16N5O13P3.xC6H15N
Target:
Apoptosis,DNA/RNA Synthesis,HBV,HIV,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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