JAK1-IN-4 is a potent and selective JAK1 inhibitor, with IC50s of 85 nM, 12.8 µM and >30 µM for JAK1, JAK2, and JAK3, respectively. JAK1-IN-4 inhibits STAT3 phosphorylation in NCI-H 1975 cells (IC50, 227 nM)[1].
Molecular Weight:
521.59
Purity:
99.26
CAS Number:
[2091134-35-7]
Formula:
C26H32FN9O2
Target:
JAK
Application Notes:
MCE Product type: Reference compound
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