L 858051 (dihydrochloride), CAS [[115116-37-5]] Preis auf Anfrage

Product Overview

• Article Name: L 858051 (dihydrochloride), CAS [[115116-37-5]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-116540A
• Supplier Catalog Number: HY-116540A
• Alternative Catalog Number: MCE-HY-116540A-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: 7DMB-Forskolin

Product Description

L 858051 (7DMB-Forskolin) dihydrochloride, an analog of Forskolin (HY-15371), is an adenylyl cyclase stimulator. L 858051 dihydrochloride directly activates adenylyl cyclase to increase intracellular, cellular, and ciliary cAMP levels. L 858051 dihydrochloride activates recombinant cyclic nucleotide-gated (E583M CNGA2) channels to induce a non-selective, Mg2+-sensitive current in adult rat ventricular myocytes. L 858051 dihydrochloride maximally stimulates L-type Ca2+ current in adult rat ventricular myocytes. L 858051 dihydrochloride increases total PDE3 and PDE4 activities in adult rat ventricular myocytes, with effects insensitive to PKA inhibition. L 858051 dihydrochloride serves as a tool to elevate intracellular cAMP for studying subsarcolemmal cAMP dynamics and compartmentation in adult rat ventricular myocytes[1][2][3].

Product Properties

• Molecular Weight: 609.62
• CAS Number: [115116-37-5]
• Formula: C29H50Cl2N2O7
• Target: Adenylate Cyclase

Application Notes

• Application Notes: MCE Product type: Reference compound