FzM1, CAS [[1680196-54-6]]

Product Overview

• Article Name: FzM1, CAS [[1680196-54-6]]
• Biozol Catalog Number: MCE-HY-116553
• Supplier Catalog Number: HY-116553
• Alternative Catalog Number: MCE-HY-116553-10MMX1ML,MCE-HY-116553-100MG,MCE-HY-116553-50MG,MCE-HY-116553-1MG,MCE-HY-116553-5MG,MCE-HY-116553-10MG,MCE-HY-116553-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

FzM1 is a negative allosteric modulator (NAM) of Frizzled receptor FZD4. FzM1 reduces WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh= 6.2). FzM1 binds to an allosteric binding site located in intracellular loop 3 (ICL3) of FZD4 and alters the conformation of the receptor, ultimately inhibiting the WNT/beta-catenin cascade[1][2].

Product Properties

• Molecular Weight: 360.43
• Purity: 98.72
• CAS Number: [1680196-54-6]
• Formula: C21H16N2O2S
• Target: Wnt,beta-catenin

Application Notes

• Application Notes: MCE Product type: Reference compound