SB-236057 is an inverse agonist of the 5-HT1B receptor that exhibits strong skeletal teratogenicity in rodents and rabbits. SB-236057 affects gene expression during embryonic development through interference with the Notch signaling pathway and interaction with r-esp1. SB-236057 induces somatic patterning and tail extension defects in rat embryos during early organogenesis[1].
Molecular Weight:
534.65
CAS Number:
[180083-49-2]
Formula:
C33H34N4O3
Target:
5-HT Receptor
Application Notes:
MCE Product type: Reference compound
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