CFMMC is a selective allosteric metabotropic glutamate receptor 1 (mGluR1) antagonist. CFMMC inhibits L-glutamate-induced intracellular Ca2+ mobilization ([Ca2+]i) in Chinese hamster ovary cells expressing recombinant human mGluR1a with an IC50 value of 50 nM. CFMMC is promising for research of various central nervous system disorders, such as schizophrenia, epilepsy, anxiety, pain, cognitive dysfunction and drug abuse[1].
Molecular Weight:
389.46
CAS Number:
[1190598-60-7]
Formula:
C22H28FNO4
Target:
mGluR
Application Notes:
MCE Product type: Reference compound
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