GyrB-IN-1 is a DNA gyrase (GyrB) inhibitor. GyrB-IN-1 shows an IC50 of 19.1 µM against Mycobacterium smegmatis GyrB ATPase activity and 21.9 µM against Mycobacterium tuberculosis GyrB DNA supercoiling activity. GyrB-IN-1 exerts antimycobacterial activity and has cytotoxicity. GyrB-IN-1 can be used for the research of tuberculosis[1].
Molecular Weight:
405.86
CAS Number:
[1870007-38-7]
Formula:
C21H12ClN3O2S
Target:
Bacterial,DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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