Anticancer agent 253 (Compound 26) has anti-cancer activity against breast cancer cells, with IC50s of 6 µM (MCF-7), 10 µM (MDA-MB-231) and 6.4 µM (4T1 cells). Anticancer agent 253 arrests cell cycle and induces mitochondria-mediated apoptosis in cancer cells. Anticancer agent 253 inhibits Akt phosphorylation in human breast and prostate cancer[1].
Molecular Weight:
500.51
CAS Number:
[1983924-33-9]
Formula:
C29H23F3N4O
Target:
Akt,Apoptosis
Application Notes:
MCE Product type: Reference compound
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