2002-H20 is an inhibitor of Abeta42-induced cytotoxicity, with the activity of reducing the cytotoxicity of Alzheimers disease Abeta peptide by binding to it. 2002-H20 protects cells and reduces Abeta toxicity by promoting fibril formation, possibly by accelerating Abeta aggregation. The screening method of 2002-H20 effectively identifies compounds that reduce Abeta toxicity and presents potential inhibitory leads[1].
Molecular Weight:
345.35
CAS Number:
[351520-91-7]
Formula:
C20H15N3O3
Target:
Amyloid-beta
Application Notes:
MCE Product type: Reference compound
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