Leucettine L41 is a potent inhibitor of dual-specificity tyrosine phosphorylation-regulated kinases (DYRKs) and CDC-like kinases (CLKs). Leucettine L41 can also inhibit GSK-3 singnaling. Leucettine L41 can inhibit cell apoptosis and ROS production. Leucettine L41 can promote beta-cell cell cycle progression, cell proliferation and increase insulin secretion. Leucettine L41 can be used for the researches of neurological disease and metabolic disease, such as Alzheimers disease (AD) and diabetes[1][2].
Molecular Weight:
307.30
Purity:
98.98
CAS Number:
[1112978-84-3]
Formula:
C17H13N3O3
Target:
Apoptosis,CDK,DYRK,GSK-3,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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