ZM 253270 is a species-selective non-peptide NK-2 receptor (NK-2R) antagonist. ZM 253270 competitively inhibits the binding of [3H]NKA to native or cloned NK-2R from hamster bladder (Ki=2 nM), but has a weaker inhibitory effect (48-fold) on the binding of [3H]NKA to cloned human NK-2R[1].
Molecular Weight:
471.94
CAS Number:
[169340-04-9]
Formula:
C22H26ClN7O3
Target:
Neurokinin Receptor
Application Notes:
MCE Product type: Reference compound
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