LY243246 ((6S)-DDATHF), the 6S diastereomer of DDATHF, is a potent competitive inhibitor of 5-phosphoribosylglycinamide formyltransferase (GAR transformylase). 6R- and 6S-diastereomers of DDATHF are remarkably similar and equiactive antimetabolites inhibitory to de novo purine synthesis[1].
Molecular Weight:
443.45
CAS Number:
[106400-18-4]
Formula:
C21H25N5O6
Target:
Antifolate
Application Notes:
MCE Product type: Reference compound
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