JI051 is a stabilizer for the Hes1-PHB2 interaction. JI051 interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity[1].
Molecular Weight:
364.44
Purity:
98
CAS Number:
[2234281-75-3]
Formula:
C22H24N2O3
Target:
Notch
Application Notes:
MCE Product type: Reference compound
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