AN-7 is an orally active histone deacetylase (HDAC) inhibitor that induces histone hyperacetylation and differentiation in vitro and in vivo, and inhibits the proliferation of human prostate 22Rv1 cancer cells. AN-7 can increase the expression of the pro-apoptotic protein Bax, reduce the expression of the anti-apoptotic protein Bcl-2, and promote apoptosis by activating caspase-3, and can be used in the study of prostate cancer[1].
Molecular Weight:
254.22
CAS Number:
[213262-83-0]
Formula:
C9H19O6P
Target:
Bcl-2 Family,Caspase,HDAC
Application Notes:
MCE Product type: Reference compound1
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