KB-141 is a potent and selective TRbeta agonist. The IC50 values are 23.9 nM and 3.3 nM for binding affinities from displacement of T3 from hTRalpha1 and hTRbeta1, respectively. KB-141 has anti-obesity, anti-diabetic, and lipid-lowering effects and can be used as an anti-cholesteremic agent in vivo[1][2].
Molecular Weight:
355.21
CAS Number:
[219691-94-8]
Formula:
C17H16Cl2O4
Target:
Thyroid Hormone Receptor
Application Notes:
MCE Product type: Reference compound
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