UK-1745 is a cardiotonic agent with vasodilating and antiarrhythmic properties. It increases intracellular levels of cyclic adenosine monophosphate (cAMP) in cardiomyocytes by inhibiting phosphodiesterase III, thereby enhancing myocardial contractility. Additionally, UK-1745 exhibits beta-adrenergic receptor blocking activity, which helps reduce the oxygen consumption of the heart and prevent calcium overload. These characteristics make UK-1745 a promising candidate for research in congestive heart failure[1][2].
Molecular Weight:
310.82
CAS Number:
[170684-14-7]
Formula:
C16H23ClN2O2
Target:
Adrenergic Receptor,Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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