LG190178 is a non-steroidal vitamin D receptor (VDR) ligand that can induce the formation of heterodimer complexes between VDR and retinoid X receptor (RXR), stabilizing the agonistic conformation of the VDR ligand-binding domain and promoting its interaction with co-activators. LG190178 has functions in regulating calcium homeostasis, bone mineralization, as well as cell proliferation, differentiation, and apoptosis, making it useful for research in psoriasis, osteoporosis, and cancer[1].
Molecular Weight:
458.63
CAS Number:
[233268-81-0]
Formula:
C28H42O5
Target:
Apoptosis,RAR/RXR,VD/VDR
Application Notes:
MCE Product type: Reference compound
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