TLSC702 is a human glyoxalase I (hGLO I) inhibitor with an IC50 of 2.0 µM. TLSC702 inhibits the activity of human glyoxalase I, thereby leading to the accumulation of methylglyoxal and its derived advanced glycation end products. TLSC702 inhibits tumor cell proliferation, induces apoptotic morphological changes, internucleosomal DNA fragmentation and PARP cleavage in tumor cells. TLSC702 can be used in research related to leukemia and lung cancer[1].
Molecular Weight:
325.38
CAS Number:
[748786-57-4]
Formula:
C18H15NO3S
Target:
Apoptosis,DNA/RNA Synthesis,Glyoxalase (GLO),PARP
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
