AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits wild type BRAF, V600E mutant BRAF and wild type CRAF, with IC50s of 79 nM, 38 nM and 68 nM, respectively. AZ304 also has significant effect on other kinases, such as p38 (IC50, 6 nM), CSF1R (IC50, 35 nM). Anti-tumor activity[1].
Molecular Weight:
451.52
Purity:
99.77
CAS Number:
[942507-42-8]
Formula:
C27H25N5O2
Target:
Autophagy,Raf
Application Notes:
MCE Product type: Reference compound
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