JC-171 is a selective NLRP3 inflammasome inhibitor, with an IC50 of 8.45 µM for inhibiting LPS/ATP-induced interleukin-1beta (IL-1beta) release from J774A.1 macrophages[1].
Molecular Weight:
384.83
Purity:
98.41
CAS Number:
[2112809-98-8]
Formula:
C16H17ClN2O5S
Target:
NOD-like Receptor (NLR)
Application Notes:
MCE Product type: Reference compound
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