4-Hydroperoxy cyclophosphamide is the active metabolite form of the precursor Cyclophosphamide. 4-Hydroperoxy cyclophosphamide cross-links DNA to induce T cell apoptosis independent of caspase receptor activation, and can activate the mitochondrial death pathway by producing reactive oxygen species (ROS). 4-Hydroperoxy cyclophosphamide can be used in the study of rheumatoid arthritis and autoimmune diseases[1][2].
Molecular Weight:
293.08
Purity:
98
CAS Number:
[39800-16-3]
Formula:
C7H15Cl2N2O4P
Target:
Apoptosis,DNA Alkylator/Crosslinker,Drug Metabolite,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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