PenCB (PCB 118) could induces pyroptosis by priming and activating NFkappaB-dependent NLRP3 inflammasome. PCB 118 induces oxidative stress and pyroptosis are dependent on Aryl hydrocarbon receptor (AhR) activation and subsequent cytochrome P450 1A1 upregulation[1].
Molecular Weight:
326.44
Purity:
99.94
CAS Number:
[31508-00-6]
Formula:
C12H5Cl5
Target:
Pyroptosis
Application Notes:
MCE Product type: Reference compound
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