ZLD10A is a highly potent and selective EZH2 inhibitor with the activity of inhibiting H3K27 methylation. ZLD10A can inhibit wild-type and mutant EZH2 with nanomolar potency and has more than 1000-fold selectivity for the other 10 histone methyltransferases. ZLD10A inhibited cell proliferation of DLBCL cell lines in a concentration- and time-dependent manner, showing a potential antiproliferative effect. ZLD10A can be used in the study of EZH2 mutant lymphomas[1].
Molecular Weight:
612.80
CAS Number:
[1782064-91-8]
Formula:
C37H48N4O4
Target:
Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound
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