NSC 23925B, CAS [[1369591-04-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-117593
Supplier Catalog Number:
HY-117593
Alternative Catalog Number:
MCE-HY-117593-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
NSC 23925B is a P-glycoprotein (P-gp) inhibitor, as well as the most biologically active isomer of NSC23925 (HY-19626), which reverses and prevents P-glycoprotein-mediated multidrug resistance in cancer cells. NSC 23925B shows weak inhibition against most CYP450 enzymes (IC50 > 10 µM), and exhibits moderate inhibitory activity against CYP2B6 and CYP2D6 with IC50 values of 8.589 µM and 1.407 µM, respectively. NSC 23925B can be used for the research of multidrug-resistant cancers[1].
Molecular Weight:
421.36
CAS Number:
[1369591-04-7]
Formula:
C22H26Cl2N2O2
Target:
Cytochrome P450,Drug Isomer,P-glycoprotein
Application Notes:
MCE Product type: Reference compound
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