UNC569 is a potent, reversible, ATP-competitive and orally active Mer kinase inhibitor with an IC50 of 2.9 nM and a Ki of 4.3 nM. UNC569 also inhibits Axl and Tyro3 with IC50s of 37 nM and 48 nM, respectively. UNC569 can be used for acute lymphoblastic leukemia (ALL) and atypical teratoid/rhabdoid tumors research[1][2]
Molecular Weight:
396.50
Purity:
99.92
CAS Number:
[1350547-65-7]
Formula:
C22H29FN6
Target:
TAM Receptor
Application Notes:
MCE Product type: Reference compound1
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